Frequent detection of viral nucleic acids in heart valve tissue.

نویسندگان

  • Oliver Donoso Mantke
  • Rudolf Meyer
  • Susanna Prösch
  • Matthias Niedrig
چکیده

Due to a paucity of published data concerning the prevalence of viral nucleic acid in homografts, we analyzed tissue from 30 donor hearts for the presence of viral genome sequences of enteroviruses, adenoviruses, human cytomegalovirus, and influenza virus using different PCR techniques. Viral DNA was amplified in 64 and 52% of the subvalvular myocardial tissue and non-coronary valve samples, respectively. These findings, compared with clinical history and histologic and serologic analysis, demonstrate the importance of viral safety measures in heart valve banking.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 5  شماره 

صفحات  -

تاریخ انتشار 2004